Reduce Seizure Frequency without Surgery or Medication

81% of tVNS® patients experienced a minimum 25% reduction of seizure frequency over a treatment period of 28 days.

Treatment with tVNS® is medication-free, has minimal side effects and does not require surgery. tVNS® is the only non-invasive vagus nerve stimulation device approved as a medical device under the EU-MDR.

Understanding Epilepsy

Empowering Epilepsy Management: Beyond Medication and Surgery with tVNS®

Epilepsy is a neurological condition that affects millions worldwide, characterized by the tendency to have recurrent seizures. These seizures are the result of sudden, excessive electrical discharges in a group of brain cells. Different parts of the brain can be the source of these seizures, which can vary in frequency and intensity, profoundly impacting an individual’s quality of life.

The Challenge of Epilepsy Medication

Traditionally, epilepsy is managed with antiepileptic drugs (AEDs) aimed at controlling or reducing the frequency of seizures. While medication is effective for many, it’s not without its challenges. A significant number of patients continue to experience seizures despite medication, and side effects of AEDs can be substantial. These can range from mild inconveniences like fatigue and dizziness to more severe impacts on mood, cognitive function, and physical health.

Invasive VNS: A Historical Overview

For those whose seizures are not well-controlled by medication, invasive Vagus Nerve Stimulation (VNS) has been a treatment option for decades. This approach requires surgical implantation of a device that sends regular, mild pulses of electrical energy to the brain via the vagus nerve. While effective for some, the invasive nature of the procedure entails risks and potential complications, from infection to vocal cord paralysis, making it a less appealing option for others.

Introducing Non-Invasive tVNS®

Our device represents a groundbreaking advancement in the treatment of epilepsy: a non-invasive form of VNS that eliminates the need for surgery. By stimulating the vagus nerve through the skin at the cymba concha—an area of the ear with direct connections to the vagus nerve—tVNS® offers a safe and user-friendly alternative. This innovative approach harnesses the therapeutic potential of VNS while significantly reducing the risk of side effects and complications associated with invasive procedures.

With tVNS®, patients have access to a novel form of epilepsy management that is both effective and minimally intrusive, reflecting our commitment to improving the lives of those living with this challenging condition.

What is tVNS®?

Non-invasive vagus nerve stimulation for the treatment of epilepsy

Transcutaneous Vagus Nerve Stimulation (tVNS®) is an innovative approach to epilepsy management that offers a non-invasive, drug-free alternative to traditional treatments.

The vagus nerve, central to our body’s nervous system, plays a critical role in maintaining homeostasis. tVNS® harnesses the therapeutic potential of this nerve through targeted stimulation of its auricular branch, accessible within the ear.

This innovative approach utilizes gentle electrical impulses to modulate the vagus nerve’s activity, encouraging a state of balance across the body’s systems. The result? A reduction in the seizure frequency in epilepsy patients, achieved through a method that avoids the invasiveness of surgery and the side effects associated with medication. 

Approved as a Class IIa medical device under the European Medical Device Regulation (MDR), tVNS® sets a new standard in the treatment of neurological conditions, offering a blend of efficacy, safety, and simplicity.

The Science Behind tVNS®

The vagus nerve plays a pivotal role in regulating several bodily functions, including the brain’s electrical excitability. By targeting the auricular branch of the vagus nerve, specifically at the cymba concha region of the ear, tVNS® delivers electrical impulses that are believed to influence the brain’s seizure threshold. This targeted stimulation can help restore a balance to the nervous system’s activity, providing a new layer of control over epilepsy symptoms.

A Non-Invasive Solution

Unlike invasive Vagus Nerve Stimulation that requires surgical implantation of a device, tVNS® offers a significant advancement in treatment accessibility and patient comfort. The tVNS® device is externally applied, making it a convenient option for daily use without the risks or downtime associated with surgery. This ease of use empowers patients with epilepsy to incorporate tVNS® therapy into their regular routine, enhancing their overall quality of life and seizure management strategy.

Why tVNS® for Epilepsy?

For individuals living with epilepsy, especially those for whom medication is not sufficiently effective or who experience significant side effects from their current treatment plan, tVNS® presents a promising alternative. It opens the door to a more holistic approach to epilepsy management, focusing on the natural capabilities of the body’s nervous system to mitigate seizure activity.

In embracing tVNS®, patients and healthcare providers are accessing a cutting-edge tool in the fight against epilepsy, one that is backed by a growing body of clinical research and real-world evidence.

tVNS® offers a new hope for those seeking to reclaim their lives from the grip of seizures.

How does treatment with tVNS® work?

You can use tVNS® anytime, anywhere. It's easy to use, portable, and discrete.​

tVNS® harnesses the power of Transcutaneous Vagus Nerve Stimulation to offer an innovative, non-invasive therapy for epilepsy. This sophisticated treatment works by applying gentle electrical impulses to the auricular branch of the vagus nerve, accessible through the cymba concha area of the ear, a site with 100% vagus nerve innervation. Here’s a closer look at the mechanism and the benefits it brings to those living with epilepsy.

Targeted Neural Modulation

The essence of tVNS® lies in its ability to modulate the nervous system’s activity directly. By targeting the vagus nerve, tVNS® influences the brain’s neural circuits involved in seizure generation and propagation. The electrical impulses delivered by the device aim to reduce the excitability of these neural networks, decreasing the likelihood of seizure occurrence.

Restoring Balance

The vagus nerve plays a crucial role in maintaining the balance of the parasympathetic and sympathetic nervous systems. tVNS® stimulates this nerve to help restore equilibrium, reducing the frequency and intensity of epileptic seizures. This equilibrium not only impacts seizure control but also promotes a sense of overall well-being, as the vagus nerve is integral to functions like mood regulation and stress response.

A Convenient and Safe Therapy

Designed for daily use, tVNS® can be easily incorporated into the patient’s lifestyle without the need for invasive procedures or the risk of significant side effects associated with conventional epilepsy treatments. The device is applied externally, making it an ideal option for patients seeking a less invasive, more manageable approach to epilepsy care.

Clinically Supported

Emerging research and clinical trials underscore the potential of tVNS® as an effective adjunct therapy for epilepsy. With each study, we gain deeper insights into how this technology can be optimized to offer greater control over seizures, enhancing the quality of life for those with epilepsy.

Better days are ahead.

With its non-invasive approach, patient-friendly treatments, and minimal side effects, tVNS® offers a new horizon of hope and relief for those living with epilepsy. Embrace a future where each day holds the promise of greater comfort and enhanced quality of life.

Certified Medical Device

tVNS® is the world's only non-invasive vagus nerve stimulation approved as a Class IIa medical device under the EU-MDR, offering a scientifically validated treatment for conditions realted to sympathovagal imbalance.

Non-Invasive Approach

A safe and gentle alternative to surgery and medication, tVNS® stimulates the vagus nerve through the skin, offering a harmonious path to wellbeing with very low side-effects.

Control at Your Fingertips

Use our innovative tVNS® device anywhere and monitor your treatment through our user-friendly app. You have the freedom to tailor your therapy to your lifestyle.

Most Effective Stimulation Site

tVNS® is the only non-invasive stimulation device that stimulates the cymba concha, resulting in 100% vagus nerve innervation (as opposed to e.g. the tragus, which only results in 45% innervation).

Why We Lead in Vagus Nerve Stimulation

For over 20 years, our commitment to innovation has positioned us at the forefront of non-invasive vagus nerve stimulation.

Our unmatched research and development efforts are backed by solid clinical trials, ensuring our devices are not only effective but also safe and reliable. As an approved Class IIa medical device under the EU-MDR, we offer scientifically validated solutions in a market crowded with unverified alternatives.

Since introducing the Cerbomed Nemos device, we’ve led the market in non-invasive vagus nerve technology. Our pioneering approach and sustained innovation keep us ahead, with our devices being preferred by healthcare professionals and researchers worldwide due to unmatched safety, reliability and precision.

Developed and manufactured in Germany, our devices meet the highest quality standards, reflecting our dedication to excellence and the well-being of our patients.

 

Download the tVNS® Patient App​

Track, monitor and share your treatment​

The innovative tVNS® Patient App is a wellness and session-diary application designed to help users keep a record of their well-being and the duration of their stimulation sessions.

The tVNS® Patient App is available now in the Google Play Store and in the Apple App Store (EU-only).

tVNS® Patient is fully compliant with the General Data Protection Regulation (GDPR), ensuring that patient data is handled with the utmost care and confidentiality.

Voices of Healing: Real Stories from tVNS® Patients​

"It's wonderful that with tVNS® I have found a treatment option for my Epilepsy that makes me feel better without needing surgery and worrying about side-effects."
Katja S.
tVNS® Patient from Munich, Germany
"Epilepsy had me always bracing for the next episode. Since integrating tVNS®, there's been a marked change in the regularity of my seizures. It's more than relief; it's empowerment."
Martin G.
tVNS® Patient from Leicester, United Kingdom

Why choose our tVNS® devices?

Our tVNS® device is the only non-invasive vagus nerve stimulator that is approved as a Class IIa medical device under the European Medical Device Regulation (EU-MDR). tVNS® sets itself apart with its non-invasive, clinically validated approach, offering a safer and more comfortable alternative to invasive methods. Uniquely targeting the cymba concha for 100% innervation of the auricular branch of the vagus nerve (ABVN) with our patented electrode, tVNS® ensures maximum efficacy compared to other devices that only achieve partial innervation.

Approved Medical Device

Our tVNS® device is the only non-invasive vagus nerve stimulation (VNS) device that is approved as a medical device under the EU-MDR. It uniquely targets the Cymba Concha for 100% innervation of the auricular branch of the vagus nerve, unlike other devices that stimulate other areas and are not manufactured under the same quality and safety standards.

Non-Surgical Approach​

tVNS® offers the efficacy of vagus nerve stimulation without the complexities or risks of surgical interventions. This means meaningful therapeutic benefits, all under your control, without invasive procedures.

Minimal Side Effects

Transitioning away from traditional medications often comes with the pursuit of fewer side effects. tVNS®, being drug-free, ensures a therapeutic experience with reduced potential for long-term adverse outcomes, positioning itself as a safer alternative.

Made in Germany

Our commitment to excellence ensures that each device meets the highest standards of quality and performance, embodying the renowned precision of German engineering and manufacturing. With tVNS®, you’re choosing a device built on a foundation of durability and innovative design, trusted by healthcare professionals and researchers worldwide.

Innovative App Integration

Tracking and understanding your treatment progression is crucial. Our dedicated tVNS® Patient App not only provides real-time monitoring but also facilitates seamless sharing of data with your healthcare professionals.

Remote Flexibility

In our modern age, the convenience of remote access is invaluable. tVNS® extends this by offering device delivery directly to your doorstep and remote training. Initiate your treatment journey without the hassles or constraints of travel.

Pediatric Compatibility

tVNS® has been meticulously designed and approved for use in children aged 3 and above, bridging a crucial gap in pediatric care.

Easy to Use

Functionality should not compromise simplicity. The tVNS® device, while technologically advanced, is as intuitive as a smartphone, making integration into daily routines effortless.

Clinical Evidence:
The Science behind tVNS®

Discover the proven effectiveness and safety of tVNS®, highlighted by pivotal clinical trials and studies. Our unique focus on cymba concha stimulation, quality control and clinical evidence, positions tVNS® as the preferred choice among researchers, ensuring we lead in neurotherapeutic innovation and patient care.

Epilepsy

After a 20 week treatment period, active tVNS® patients recorded an average 34.2% reduction of seizure frequency.

Take the next step with tVNS® - for a life without limitations.

Every day presents an opportunity. Yet, for those navigating the challenges of medical conditions, some days can feel overshadowed by discomfort or uncertainty. With tVNS®, we aim to bring a brighter shade to every day. By harnessing the power of neurostimulation, our tVNS® device aims to pave the way for more pain-free days, empowering patients to lead self-determined lives. It’s not merely about symptom relief, it’s about reclaiming the essence of each day, savoring moments with loved ones, and pursuing passions without being held back by your condition.

Get in Touch with Our Experts

Contact our tVNS® Customer Service Team to learn more about tVNS® and receive personalized information and support, and begin your journey towards better health with tVNS®.

Your tVNS® Expert:

Jörg Trinkwalter