Drug-Free
Non-Invasive
Epilepsy Treatment
Treatment with tVNS® can significantly reduce your seizure frequency and intensity – without surgery, medication, and with minimal side effects.
tVNS® is the only non-invasive vagus nerve stimulation device approved as a medical device under the EU-MDR that is approved to treat Epilepsy.
tVNS® users experienced an average 34.2% reduction in seizure frequency over a treatment period of 20 weeks.
Bauer S, et al. Transcutaneous Vagus Nerve Stimulation (tVNS) for Treatment of Drug-Resistant Epilepsy: A Randomized, Double-Blind Clinical Trial (cMPsE02). Brain Stimul. 2016 May-Jun; doi: 10.1016/j.brs.2015.11.003. PMID: 27033012.
What is Epilepsy?
Epilepsy is a neurological condition that affects millions worldwide, characterized by the tendency to have recurrent seizures. These seizures are the result of sudden, excessive electrical discharges in a group of brain cells. Different parts of the brain can be the source of these seizures, which can vary in frequency and intensity, profoundly impacting an individual’s quality of life.
The Challenge of Epilepsy Medication
Traditionally, epilepsy is managed with antiepileptic drugs (AEDs) aimed at controlling or reducing the frequency of seizures. While medication is effective for many, it’s not without its challenges. A significant number of patients continue to experience seizures despite medication, and side effects of AEDs can be substantial. These can range from mild inconveniences like fatigue and dizziness to more severe impacts on mood, cognitive function, and physical health.
Invasive VNS: A Historical Overview
For those whose seizures are not well-controlled by medication, invasive Vagus Nerve Stimulation (VNS) has been a treatment option for decades. This approach requires surgical implantation of a device that sends regular, mild pulses of electrical energy to the brain via the vagus nerve. However, the procedure requires surgery, posing risks such as infection and complications. Side effects like voice changes and coughing are common, and only 50-60% of patients respond to treatment. Additionally, the battery must be surgically replaced every five years.
Introducing Non-Invasive tVNS®
Our tVNS® device represents a groundbreaking advancement in the treatment of epilepsy: a non-invasive form of VNS that eliminates the need for surgery. By stimulating the vagus nerve through the skin at the cymba concha—an area of the ear with direct connections to the vagus nerve—tVNS® offers a safe and user-friendly alternative. This innovative approach harnesses the therapeutic potential of VNS while significantly reducing the risk of side effects and complications associated with invasive procedures.
With tVNS®, patients have access to a novel form of epilepsy management that is both effective and minimally intrusive, reflecting our commitment to improving the lives of those living with this challenging condition.
Non-invasive vagus nerve stimulation for the treatment of epilepsy
Transcutaneous Vagus Nerve Stimulation (tVNS®) is an innovative approach to epilepsy management that offers a non-invasive, drug-free alternative to traditional treatments.
The vagus nerve, central to our body’s nervous system, plays a critical role in maintaining homeostasis. tVNS® harnesses the therapeutic potential of this nerve through targeted stimulation of its auricular branch, accessible within the ear.
This innovative approach utilizes gentle electrical impulses to modulate the vagus nerve’s activity, encouraging a state of balance across the body’s systems. The result? A reduction in the seizure frequency in epilepsy patients, achieved through a method that avoids the invasiveness of surgery and the side effects associated with medication.
Approved as a Class IIa medical device under the European Medical Device Regulation (MDR), tVNS® sets a new standard in the treatment of neurological conditions, offering a blend of efficacy, safety, and simplicity.
You can use tVNS® anytime, anywhere. It's easy to use, portable, and discrete.
tVNS® delivers targeted neurostimulation therapy designed specifically to manage epilepsy by engaging the vagus nerve’s ability to modulate brain activity. This innovative treatment stimulates the auricular branch of the vagus nerve (ABVN) via the skin using gentle, precise electrical impulses. These signals first reach the brain stem and then ascend to higher brain centers, aiming to correct the dysregulation associated with epilepsy.
Designed for daily life, tVNS® is easy to use, portable, and discreet, enabling integration into your daily routine without disruption. Whether you’re at home, at work, or on the go, tVNS® offers a reliable and accessible way to reduce seizure frequency and improve quality of life.
Each session promotes a step towards neurological balance, utilizing the body’s own pathways to enhance overall wellbeing. The user-friendly nature of the tVNS® device ensures that beginning and continuing treatment is simple, empowering you to manage your epilepsy effectively and non-invasively.
Sustained seizure freedom in a 24-year-old patient after treatment with our tVNS® device
In the journal Seizure: European Journal of Epilepsy, the following case study demonstrates the effective use of transcutaneous vagus nerve stimulation (tVNS®) in achieving sustained seizure freedom in a patient with drug-resistant epilepsy caused by subcortical band heterotopias.
The patient, who had experienced epilepsy since childhood and had poor control over seizures with multiple medications, found significant improvement with tVNS®. Initiated after other treatments failed to maintain seizure control, tVNS® led to an absence of seizures for over 56 months at the time of reporting. This case highlights tVNS® as a promising non-pharmaceutical option, emphasizing its potential as an adjunctive treatment in managing drug-resistant forms of epilepsy.
Better days are ahead.
With its non-invasive approach, patient-friendly treatments, and minimal side effects, tVNS® offers a new horizon of hope and relief for those living with epilepsy. Embrace a future where each day holds the promise of greater comfort and enhanced quality of life.
Certified Medical Device
tVNS® is the world’s only non-invasive vagus nerve stimulation approved as a Class IIa medical device under the EU-MDR, that is indicated to treat epilepsy.
Non-Invasive Approach
Control at Your Fingertips
Most Effective Stimulation Site
Why We Lead in Vagus Nerve Stimulation
For over 20 years, our commitment to innovation has positioned us at the forefront of non-invasive vagus nerve stimulation.
Our unmatched research and development efforts are backed by solid clinical trials, ensuring our devices are not only effective but also safe and reliable. As an approved Class IIa medical device under the EU-MDR, we offer scientifically validated solutions in a market crowded with unverified alternatives.
Since introducing the Cerbomed Nemos device, we’ve led the market in non-invasive vagus nerve technology. Our pioneering approach and sustained innovation keep us ahead, with our devices being preferred by healthcare professionals and researchers worldwide due to unmatched safety, reliability and precision.
Developed and manufactured in Germany, our devices meet the highest quality standards, reflecting our dedication to excellence and the well-being of our patients.
Track, monitor and share your treatment
The innovative tVNS® Patient App is a wellness and session-diary application designed to help users keep a record of their well-being and the duration of their stimulation sessions.
The tVNS® Patient App is available now in the Google Play Store and in the Apple App Store (EU-only).
tVNS® Patient is fully compliant with the General Data Protection Regulation (GDPR), ensuring that patient data is handled with the utmost care and confidentiality.
Voices of Progress:
Real Stories from tVNS® Patients
"It's wonderful that with tVNS® I have found a treatment option for my Epilepsy that makes me feel better without needing surgery and worrying about side-effects."
Katja S.
tVNS® Patient from Munich, Germany
"Epilepsy had me always bracing for the next episode. Since integrating tVNS®, there's been a marked change in the regularity of my seizures. It's more than relief, it's empowerment."
Martin G.
tVNS® Patient from Leicester, UK
Why choose our
tVNS® devices?
Approved Medical Device
Our tVNS® device is the only non-invasive vagus nerve stimulation (VNS) device that is approved as a medical device under the EU-MDR. It uniquely targets the Cymba Concha for 100% innervation of the auricular branch of the vagus nerve, unlike other devices that stimulate other areas and are not manufactured under the same quality and safety standards.
Non-Surgical Approach
tVNS® offers the efficacy of vagus nerve stimulation without the complexities or risks of surgical interventions. This means meaningful therapeutic benefits, all under your control, without invasive procedures.
Minimal Side Effects
Transitioning away from traditional medications often comes with the pursuit of fewer side effects. tVNS®, being drug-free, ensures a therapeutic experience with reduced potential for long-term adverse outcomes, positioning itself as a safer alternative.
Made in Germany
Our commitment to excellence ensures that each device meets the highest standards of quality and performance, embodying the renowned precision of German engineering and manufacturing. With tVNS®, you’re choosing a device built on a foundation of durability and innovative design, trusted by healthcare professionals and researchers worldwide.
Innovative App Integration
Tracking and understanding your treatment progression is crucial. Our dedicated tVNS® Patient App not only provides real-time monitoring but also facilitates seamless sharing of data with your healthcare professionals.
Remote Flexibility
In our modern age, the convenience of remote access is invaluable. tVNS® extends this by offering device delivery directly to your doorstep and remote training. Initiate your treatment journey without the hassles or constraints of travel.
Pediatric Compatibility
tVNS® has been meticulously designed and approved for use in children aged 3 and above, bridging a crucial gap in pediatric care.
Easy to Use
Functionality should not compromise simplicity. The tVNS® device, while technologically advanced, is as intuitive as a smartphone, making integration into daily routines effortless.
Take the next step with tVNS® - for a life without limitations.
Every day presents an opportunity. Yet, for those navigating the challenge of living with epilepsy, some days can feel overshadowed by discomfort or uncertainty. With tVNS®, we aim to bring a brighter shade to every day.
By utilizing the power of neurostimulation, our tVNS® device aims to pave the way for more seizure-free days, empowering patients to lead self-determined lives.
Get in Touch with Our Experts
Contact our tVNS® Customer Service Team to learn more about tVNS® and receive personalized information and support, and begin your journey towards better health with tVNS®.
